Keeping comfort in mind

Less than 1mm in size, the MicronJet™ microneedle offers an easy-to-use*, consistent4-9 and efficient intradermal alternative for practically painless8,9 delivery of drugs and vaccines. It can be used with any standard syringe to inject liquid substances directly into the skin, including vaccines, drugs, peptides and dermal fillers.
*User study; data on file.

Research shows that by harnessing the robust immune system of the skin,
intradermal delivery with MicronJet™ can achieve better immunological results than intramuscular and subcutaneous delivery, with lower doses.

NEARLY PAINLESS

PRACTICALLY PAINLESS 1-8,9

LESS INTIMIDATING THAN REGULAR NEEDLE AND SYRINGE

LESS INTIMIDATING THAN REGULAR NEEDLE AND SYRINGE1,8

STUDIED IN INFANTS

TESTED IN WIDE AGE RANGE (PROVEN SAFETY AND IMMUNOGENICITY IN INFANTS AND ELDERLY) 7

Improved Immunogenicity and dose sparing over subcutaneous and intramuscular delivery1-8,10

The skin is one of the most potent immune organs of the body, naturally evolved for fighting pathogens However, injecting vaccines into the skin with a regular needle (using the Mantoux technique) is technically difficult.

The easy-to-use MicronJetTM has demonstrated:

  • Improved immunogenicity to full-dose vaccines (seasonal influenza, zoster)2,3,5,8
  • Significant dose sparing (4-40% of the dose) with various vaccines (seasonal and pandemic influenza, zoster, polio)1-8,10
  • Adjuvant sparing in seasonal influenza10

Improved immunogenicity/potency over other intradermal devices

NanoPass clinical trials have shown superior clinical outcomes over other intradermal devices in tests with different vaccinations

  • Improved immunogenicity over intradermal delivery using the Mantoux technique attributed to the shallowness and consistency of injection3
  • Better potency over Intanza®9, delivering the same results with one third of the dose5

Consistent and shallow intradermal delivery

The easy to use MicronJetTM provides one of most shallow and consistent forms of intradermal delivery. Its minute size (0.6mm) allows for shallow injection. Being barely visible to the naked eye makes it also significantly less painful than regular injections, as well as much less intimidating. It requires a short learning curve, enabling practitioners to quickly learn how to use the device, and adopt it as a leading alternative.

  • Blebs of >6 mm were observed 99% of the time, evaluated in over 1,000 injections on more than 800 subjects4-9
  • Significantly less painful and intimidating than a regular needle and syringe, with the potential for improved compliance1,8,9
  • Pediatrics applicability, as demonstrated by large Phase III study on 6-week-old infants7
  • Smallest hollow needle in the market allows for a practically painless injection1,8,9

3 Simple Application Steps illustrations

3 Simple Application Steps
3 Simple Application Steps
3 Simple Application Steps

Frequently Asked Questions

Q. What should I do in case of leakage?
A. Follow the common practice as with a regular needle and syringe

Q. What are the main causes of major leakage?
A. Injection may have started out wet – avoid pressing the plunger prior to injection
A. Syringe not held properly – make sure you hold the syringe flanges between fingers and thumb (see figure No. 2); avoid switching hands
A. Improper device orientation – make sure blue line faces you during injection and syringe is not tilted sideways or rotated (see figure No. 2)
A. Too high / low injection angle – make sure angle between syringe axis and skin surface is as close as possible to 45˚
A. Insufficient pressure applied to the skin – increase slightly
A. Skin not stretched – make sure to keep the skin stretched throughout the entire injection

Q. What are the causes of small/no bleb without leakage?
A. Large air bubble within syringe – make sure to fill syringe properly and remove air bubbles
A. The fluid is leaking between the device and the syringe – make sure you firmly connect the device to the syringe

Q. What are the causes of high injection pressure?
A. Too much pressure is applied to the skin – reduce slightly
A. Improper injection angle – too high. Make sure angle between syringe axis and skin surface is as close as possible to 45˚
A. Skin type or texture – try different injection site

Intradermal vaccination is safe.
Over the years, intradermal vaccination has been proved to be very safe with only minor adverse effects. Studies have found that intradermal vaccination may be associated with a greater incidence of local reactogenicity that typically resolves quickly. Adverse events primarily include local mild pain, swelling, and redness, but no systemic reactions*

For adverse events and contraindications and Warnings and precautions please see MicronJetTM Instruction For Use

* User study; data on file
** Marra F, Young F et al. meta analysis of intradermal versus intramuscular influenza vaccines: immunogenicity and adverse events. Influenz Other Respir Viruses 2013; 7:584-603;
*** Micronjet600 Instructions For Use