Intradermal delivery is safe

Over the years, intradermal vaccination has been proved to be very safe with only minor adverse effects.

Studies have found that intradermal vaccination may be associated with a greater incidence of local reactogenicity that typically resolves quickly.

Adverse events primarily include local mild pain, swelling, and redness, but no systemic reactions*

For Adverse Events and Contraindications and Warnings and Precautions please see MicronJetTM Instruction for Use

*Marra F, Young F et al. meta-analysis of intradermal versus intramuscular influenza vaccines: immunogenicity and adverse events. Influenza Other Respir Viruses 2013; 7:584-603;


Extensive clinical experience

Wide range of clinical trials with a variety of vaccines and drugs

One of the largest intradermal vaccination databases in industry

Numerous Trials

In addition to global commercial sales, NanoPass’s MicronJetTM Technology has been used to administer over 28,000 injections to approximately 6,500 patients in nearly 60 completed and ongoing clinical trials

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Validated Benefits

MicronJetTM has demonstrated a superior immune response with full dose2,3,5, 8,10 and equivalence or a trend for superiority with lower doses (4-40%)1-8,10

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Consistent and shallow intradermal delivery

Due to its unique design the MicronJetTM– microneedle is one of the shallowest and most consistent forms of intradermal delivery4-9  

The easy-to-use MicronJetTM provides one of most shallow and consistent forms of intradermal delivery.

Its minute size (0.6mm) allows for shallow injection. Being barely visible to the naked eye makes it also significantly less painful than regular injections, as well as much less intimidating.

It requires a short learning curve, enabling practitioners to quickly learn how to use the device, and adopt it as a leading alternative.

  • Blebs of >6 mm were observed 99% of the time, evaluated in over 1,000 injections on more than 800 subjects4-9
  • Significantly less painful and intimidating than a regular needle and syringe, with the potential for improved compliance1, 8, 9
  • Pediatrics applicability, as demonstrated by large Phase III study on 6-week-old infants7
  • Smallest hollow needle in the market allows for a practically painless injection1, 8, 9

Practically pain free injection

As the smallest hollow needle in the market (just 0.6mm long), MicronJetTM microneedle allows for a practically painless intradermal injection8-9  

When it comes to microneedles, its all about the size.

Keeping comfort in mind

Practically painless1,8,9
Less intimidating than regular vaccination needle and syringe1,8
Tested in wide age range (proven safety and immunogenicity in infants and elderly)7

The device is commercially available with regulatory approvals in multiple territories and most major markets including the US, EU, South Korea, China, Brazil and more.

3 Simple Application Steps illustrations

Question and Answers

  • What should I do in case of leakage?
    • Follow the common practice as with a regular needle and syringe
  • What are the main causes of major leakage?
    • Injection may have started out wet – avoid pressing the plunger prior to injection
    • Syringe not held properly – make sure you hold the syringe flanges between fingers
    • and thumb; avoid switching hands
    • Improper device orientation – make sure blue line faces you during injection and
    • Syringe is not tilted sideways or rotated
    • Too high / low injection angle – make sure angle between syringe axis and skin surface is as close as possible to 45˚
    • Insufficient pressure applied to the skin – increase slightly
    • Skin not stretched – make sure to keep the skin stretched throughout the entire injection
  • What are the causes of small/no bleb without leakage?
    • Large air bubble within syringe – make sure to fill syringe properly and remove air bubbles
    • The fluid is leaking between the device and the syringe – make sure you firmly connect the device to the syringe
  • What are the causes of high injection pressure?
    •  Too much pressure is applied to the skin – reduce slightly
    • Improper injection angle – too high. Make sure angle between syringe axis and skin surface is as close as possible to 45˚
    • Skin type or texture – try different injection site

Video Gallery

How to perform a MicronJetTM injection

The beauty of a MicronJetTM injection into the air