Keeping comfort in mind

Less than 1mm in size, the MicronJet600 microneedle offers an easy-to-use*, consistent4-9 and efficient intradermal alternative for nearly8,9 painless delivery of drugs and vaccines.
It can be used with any standard syringe to inject liquid substances directly into the skin, including vaccines, drugs, peptides and dermal fillers.
Research shows that by harnessing the robust immune system of the skin, intradermal delivery with MicronJet600 can achieve better immunological results than intramuscular and subcutaneous delivery, with lower doses.

NEARLY PAINLESS

NEARLY PAINLESS 1-8,9

LESS INTIMIDATING THAN REGULAR NEEDLE AND SYRINGE

LESS INTIMIDATING THAN REGULAR NEEDLE AND SYRINGE1,8

STUDIED IN INFANTS

STUDIED IN INFANTS7

Improved Immunogenicity and dose sparing over subcutaneous and intramuscular delivery1-8,10

The skin is one of the most potent immune organs of the body, fighting pathogens throughout evolution. However, injecting vaccines into the skin with a regular needle (using the Mantoux technique) is technically difficult.

The easy-to-use, 0.6mm MicronJet600 has demonstrated:

  • Improved immunogenicity to full-dose vaccines (seasonal influenza, zoster)2,3,5,8
  • Significant dose sparing (4-40% of the dose) with various vaccines (seasonal and pandemic influenza, zoster, polio)1-8,10
  • Adjuvant sparing in seasonal influenza10

Improved immunogenicity/potency over other intradermal devices

NanoPass clinical trials have shown superior clinical outcomes over other intradermal devices in tests with different vaccinations

  • Improved immunogenicity over intradermal delivery using the Mantoux technique attributed to the shallowness and consistency of injection3
  • Better potency over Intanza®9, delivering the same results with one third of the dose5

Consistent and shallow intradermal delivery

The easy to use MicronJet600 provides one of most shallow and consistent forms of intradermal delivery. Its minute size (0.6mm) allows for shallow injection. Being barely visible to the naked eye makes it also less painful than regular injections, as well as much less intimidating. It requires a short learning curve, enabling practitioners to quickly learn how to use the device, and adopt it as a leading alternative.

  • Blebs of >6 mm were observed 99% of the time, evaluated in over 1,000 injections on more than 800 subjects4-9
  • Less painful and intimidating than a regular needle and syringe, with the potential for improved compliance1,8,9
  • Pediatrics applicability, as demonstrated by large Phase III study on 6-week-old infants7
  • Smallest hollow needle in the market allows for a nearly painless injection1,8,9

Adverse effects of intradermal vaccination

Overall, intradermal vaccination has been demonstrated to be very safe. Studies have shown that intradermal vaccination may be associated with a greater incidence of local reactogenicity that typically resolves quickly. Adverse events primarily include local mild pain, swelling, and redness y, but no systemic reactions**

Adverse effects of MicronJet600

Local adverse reactions, including edema, erythema and discoloration of skin at the injection site have been observed, most likely related to the injected substance, and not to the MicronJet600.
Adverse reactions related to use of the MicronJet600 include small risk of micro bleeding (self-limiting blood dotting, ceasing within normal clotting time). Other potential device related adverse events may rarely include local infection at the injection site.***

3 Simple Application Steps illustrations

3 Simple Application Steps
3 Simple Application Steps
3 Simple Application Steps

* User study; data on file
** Marra F, Young F et al. meta analysis of intradermal versus intramuscular influenza vaccines: immunogenicity and adverse events. Influenz Other Respir Viruses 2013; 7:584-603;
*** Micronjet600 Instructions For Use