NanoPass Microneedles Technologies
 
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About the Technology

Microneedles are manufactured by using MEMS (Micro Electro Mechanical Systems) technology and are made of pure silicon crystals. Not to be confused with silicone oil or rubber, the silicon crystal is one of earth's chemical elements and is pure and robust. Using MEMS technology has enabled the creation of elaborate miniature devices with unprecedented mechanical stability and structural precision.

NanoPass MicroPyramid arrays are manufactured in industrial clean rooms, using a high-precision production process.

 

Based on its Microneedles technology, NanoPass currently produces hollow microneedles for intradermal injections and solid microprojections for cosmetic enhancement.

 

Robust Design
 
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Enlarged up to 750 times its original size by electron microscopy, MicroPyramid microneedles have a robust and a sharp architecture.

 
 
Intradermal delivery

 

Vaccine dose sparing with intradermal delivery

Intradermal vaccine delivery has been repeatedly shown to allow significant dose sparing when compared to conventional administration methods such as intramuscular and subcutaneous administration. This effect is attributed to the relatively dense network of immune cells present in the skin.

 

For further reference on vaccine dose sparing with intradermal delivery see:
 
Safety and efficacy of a novel microneedle device for dose sparing intradermal influenza vaccination in healthy adults. Van Damme P, Oosterhuis-Kafeja F, Van der Wielen M, Almagor Y, Sharon O, Levin Y. Vaccine. 2009 Jan 14;27(3):454-9. Epub 2008 Nov 18.
 

 

 

Microneedles for Intradermal delivery

 

NanoPass Microneedles offer a significant edge over current methods of intradermal delivery:

  1. Non Intimidating - barely visible to the naked eye, microneedle devices are ideal for children and needle-phobic patients.
  2. Delivery of Viscous Material - despite their miniature size, the Microneedles mechanical properties allow the delivery of highly viscous materials, including gelatinous substances*.

 * Data On File

News
02/09/2009
IDRI to Use NanoPass Microneedle Technology
27/08/2009
NanoPass Makes its MicronJet Technology Available to Increase Global Supply

Business Opportunities
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